目的：探讨不同性别血管痉挛性心绞痛患者的临床特征。方法：回顾性分析复旦大学附属中山医院心内科2003年1月至2013年12月住院的114例血管痉挛性心绞痛患者的临床资料，根据性别分为两组：男性组（ n＝99）和女性组（ n＝15），比较两组的危险因素、临床表现、心电图、超声心动图和冠脉造影等的差异。结果：男性患者的吸烟比例高于女性（75．8％vs 6．7％，P＜0．001），尿酸水平升高[（350．6±96．2）μmol／L vs （249．1±63．1）μmol／L ，P＜0．001]，高密度脂蛋白胆固醇降低[（1．09 ± 0．29） mmol／L vs （1．30 ± 0．35） mmol／L ，P＝0．02]。两组患者间其他危险因素、临床表现和冠状动脉造影表现等差异无统计学意义。结论：与女性相比，男性冠状动脉痉挛患者具有吸烟、高尿酸及高密度脂蛋白胆固醇水平较低的特点。%Objective:To investigate the gender specific differences clinical characteristics of coronary spasm angina patients by comparing differences of the risk factors ,clinical manifestations and coronary angiography with different gender . Methods:The clinical data of 114 patients with coronary spasm angina admitted to Zhongshan Hospital ,Fudan University from January 2003 to December 2013 were retrospectively analyzed .The patients were divided into two groups according to gender:male group (n= 99) and female group (n= 15) .The differences of the risk factors ,clinical manifestations and coronary angiography between these two groups were compared . Results: The percentage of smoking patients in the male group (75 .8% ) was higher than that in the female group (6 .7% , P< 0 .001) .Similarly ,higher uric acid levels ([350 .6 ± 96 .2]μmol/L vs [249 .1 ± 63 .1] μmol/L , P< 0 .001) and lower high density lipoprotein-cholesterol ([1 .09 ± 0 .29] mmol/L vs [1 .30 ± 0 .35] mmol/L , P= 0 .02) were also found in the male group .No statistically significant differences were found between the two groups in other risk factors ,clinical manifestations or coronary angiography .Conclusions:Male coronary spasm angina patients seemed to more smoke ,have higher uric acid levels ,and lower high density lipoprotein-cholesterol levels than female patients .
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