Objective:To study the independent prognosis factors of gastric cancer. Methods- A retrospective clinical analysis was made in 135 cases of gastric cancer, all the patients were treated by radical gastrectomy in Zhongshan Hospital from Dec. 1999 to Dec. 2005. Kaplan-Meier survival curve was applied for survival analysis,and Log-rank test was used for univariate a-nalysis. The Cox proportional hazard model was used for multivariate analysis. Results: The univariate analysis revealed that tumor location, Borrmann type, depth of invasion, lymph node metastasis, TNM stage were influential factors for the prognosis of patients(P<0. 05). The multivariable Cox regression showed that TNM stage, lymph node metastasis were independent prognostic factors of gastric cancer(P<0. 05). Conclusions: TNM stage is influential factor for the prognosis of gastric cancer.%目的:探讨影响胃癌根治术术后的预后的相关因素.方法:回顾分析复旦大学附属中山医院普外科1999年12月-2005年12月135例胃癌根治手术患者的临床资料,用Kaplan-Meier计算3年生存率,行Log-rank单因素分析、Cox回归多因素分析探讨影响胃癌患者预后因素.结果:单因素分析显示:肿瘤部位、Borrmann分型、浸润深度、淋巴结转移、TNM分期、手术方式等影响因素与预后相关(P＜0.05),多因素分析显示:TNM分期、淋巴结转移为影响胃癌患者生存的独立预后因素(P＜0.05).结论:TNM分期是影响胃癌患者预后的重要因素.
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