首页> 中文期刊> 《中国比较医学杂志》 >广东省实验用小型猪主要病原微生物学及寄生虫学调查

广东省实验用小型猪主要病原微生物学及寄生虫学调查

         

摘要

Objective To conduct a microbiological and parasitological investigation of experimental minipigs in Guangdong province. Methods Four major experimental minipig production units in Guangdong province were included in this investigation. Samples were taken from a total of 154 pigs of 4 brreds, i. e. , Bama minipigs, Juema minipigs, Tibet minipigs and Wuzhishan minipigs. Pig fur, scales, serum, rectal swabs and feces samples were collected for detection of 20 pathogens. The data were analyzed and compared among the production units and breeds. Results Mixed infections were detected in all the four institutions. The infection rates of 7 pathogens were rather high: Streptococcus suis type 2 (50. 7%), Actinobacillus pleuropneumoniae (40. 3%), Mycoplasma hyopneumoniae (100%), Japanese encephalitis virus (41. 3%), porcine circovirus type 2 (74. 8%), porcine transmissible gastroenteritis virus (73. 8%),gastroenteritis virus (44. 7%). Porcine parvovirus (26. 0%), pseudorabies virus(15. 6%) and intestinal worms (3. 2%) were also detected in some animals. The immune qualified rates of classical swine fever virus (62. 8%) and foot-and-mouth disease virus (35. 8%) were rather low. The immune qualified rate of pseudorabies virus was as high as 98. 4%. Besides, Salmonella, Brucella, swine dysentery snake like spirochetes, dermatophytes, influenza virus. Toxoplasma gondii, ectoparasites, and coccidia were not detected. Conclusions The results of this investigation indicate that epidemiological quality control of pathogens in experimental minipigs and efforts to establish high grade minipig population in Guangdong province remain to be strengthened. Our study also provides a basis for revision of local and even national standards for experimental minipigs.%目的 调查广东省实验用小型猪主要病原微生物和寄生虫的感染情况.方法 从广东省4家生产单位随机抽取小型猪154头,包括巴马小型猪、蕨麻小型猪、西藏小型猪和五指山小型猪4种品系,采集皮毛、鳞屑、血清、肛拭子、粪便等样品检测20种病原,对结果进行生产单位和品系间的差异性分析.结果 所检4家单位的所有品系小型猪均存在多种病原复合感染,猪链球菌2型(50.7%)、胸膜肺炎放线杆菌(40.3%)、肺炎支原体(100.0%)、乙型脑炎病毒(41.3%)、猪圆环病毒2型(74.8%)、猪传染性胃肠炎病毒(73.8%)、猪繁殖与呼吸综合征病毒(44.7%)7种病原的检出率相对较高,猪细小病毒(26.0%)、猪伪狂犬病病毒(15.6%)、肠道中蠕虫(3.2%)有一定检出率;要求强免的猪瘟病毒(62.8%)、口蹄疫病毒(35.8%)免疫合格率较低,猪伪狂犬病病毒免疫合格率高达98.4%.本次调查未检出沙门氏菌、布鲁氏菌、猪痢疾蛇样螺旋体、皮肤病原真菌、甲型流感病毒、弓形虫、体外寄生虫和粪便球虫.结论 广东地区存栏实验用小型猪存在多种病原复合感染,需加强免疫和质量控制,逐步建立高等级群体;同时也为实验用小型猪地方标准乃至国家标准的制/修订提供了依据.

著录项

  • 来源
    《中国比较医学杂志》 |2017年第10期|69-7379|共6页
  • 作者单位

    广东省实验动物监测所,广州 510663;

    广东省实验动物重点实验室,广州 510663;

    广东省实验动物监测所,广州 510663;

    广东省实验动物重点实验室,广州 510663;

    广东省实验动物监测所,广州 510663;

    广东省实验动物重点实验室,广州 510663;

    广东省实验动物监测所,广州 510663;

    广东省实验动物重点实验室,广州 510663;

    广东省实验动物监测所,广州 510663;

    广东省实验动物重点实验室,广州 510663;

    广东省实验动物监测所,广州 510663;

    广东省实验动物重点实验室,广州 510663;

  • 原文格式 PDF
  • 正文语种 chi
  • 中图分类 实验医学、医学实验;
  • 关键词

    实验用小型猪; 病原菌; 病毒; 寄生虫; 调查;

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