The relation of plasma haptoglobin concentration to symptomatic cerebral vasospasm (SCVS) after subarachnoid hemorrhage (SAH) was investigated.The plasma concentration of haptoglobin was analyzed by enzyme-linked immunosorbent assay (ELISA).SCVS was determined by aggravated headache,deteriorated conscious state a few days after ictus or by new neurologic impairment and new ischemic injuries on repeated CT scans.The mean concentration of plasma haptoglobin in 19 patients with SCVS was (0.29 ± 0.14) g/L,whereas it was (0.78 ± 0.48) g/L in 24 patients without SCVS.These findings may suggest that plasma haptoglobin concentration seems to be associated with the development of SCVS after SAH.%探讨蛛网膜下隙出血患者血浆触珠蛋白表达变化与症状性脑血管痉挛间的关系.共观察43例自发性蛛网膜下隙出血患者,其中19例于发病后3～14天出现症状性脑血管痉挛,酶联免疫吸附试验显示血浆触珠蛋白水平[(0.29±0.14) g/L]低于24例无症状性脑血管痉挛患者[(0.78±0.48) g/L],差异有统计学意义(t=4.848,P=0.000).提示蛛网膜下隙出血后血浆触珠蛋白水平降低可能与症状性脑血管痉挛发生有关.
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