目的:通过TNF-α、IL-6的变化,观察大柴汤对实验性大鼠全身炎症反应综合征(SIRS)的影响,并探讨其可能机制.方法:将大鼠分为造模组和治疗组,建立大鼠SIRS模型,分别检测2组大鼠不同时段的TF-α,IL-6水平变化及生存率和死亡率,并比较差别.结果:治疗组的丁NF-α、IL-6水平较造模组明显下降,且具有显著性差异(P<0.05).结论:柴黄汤具有抑制过度炎症反应,改善病情的严重程度的作用.%Objective: To observe the changae of blood TNF-a and IL-6 and to explore the effect of Chaihuang soup on systemic inflamatory response syndrome in rats and mechenism. Meth ods: Rats were randomly divided into 3 groups; normal group, SIRS group, Chaihuang soup treatment group, the contents of plasmas TNF and IL-6 were measured. Result: Compared to normal group, the contents of SIRS group TNF and IL-6 were significantly increased. Compared to SIRS group, the content of treatment group TNF and IL-6 were significantly decreased. Conclusion: Chaihuang soup can suppress inflammation reaction.
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