Objective To observe the recent therapeutic effects of small incision minimally invasive transforaminal lumbar interbody fusion ( TLIF) on single segmental lumbar degenerative disease .Methods 120 patients with single segmen-tal lumbar degenerative disease were randomly divided into 2 groups, 60 cases in the control group took traditional open trans-foraminal lumbar inter-body fusion treatment , observation group of 60 cases received minimally invasive transforaminal lumbar inter-body fusion treatment , compared 2 groups of patients ’ JOA score and evaluated the life quality of patients with lumbar spine.Results Observation group patients ’ operation time is longer than that of the control group [(149.3 ±23.2) min vs. (128.4 ±24.7) min, P <0.05],but its operation blood loss , length of incision and the average days of hospitalization were significantly lower than that of control group ( P <0.05);2 months after treatment, the observation group patients quality of life score was significantly higher than that in control group [(75.4 ±8.2)points vs.(59.5 ±7.7)points, P <0.05],JOA scores of the 2 groups were all improved ( P <0.05),and the lumbar JOA in observation group after treatment was also higher than that of the control group [(26.6 ±2.8)points vs.(18.5 ±2.4)points, P <0.05].Conclusion Effect of minimally in-vasive small incision transforaminal lumbar interbody fusion for the treatment of single segment lumbar degenerative diseases is good, worthy of clinical choice .%目的：观察微创小切口经椎间孔腰椎椎间融合（ TLIF）治疗单节段腰椎退变疾病的近期疗效。方法将收治并确诊的120例单节段腰椎退变疾病患者随机分为2组，对照组60例采取传统开放椎间孔腰椎椎间融合治疗，观察组60例采取微创小切口经椎间孔腰椎椎间融合治疗，比较2组患者在手术住院方面的差异，同时评价患者生活质量、腰椎JOA评分。结果观察组患者手术时间长于对照组[（149浇．3±23．2） min vs．（128．4±24．7） min， P ＜0．05]，但其手术失血量、平均切口长度及住院天数均显著优于对照组（ P ＜0．05）；治疗后2个月，观察组患者生活质量评分显著高于对照组[（75．4±8．2）分vs．（59．5±7．7）分， P ＜0．05]；2组腰椎JOA评分均改善（ P ＜0．05），且观察组治疗后高于对照组[（26．6±2．8）分vs．（18．5±2．4）分， P ＜0．05]。结论微创小切口经椎间孔腰椎椎间融合治疗单节段腰椎退变疾病疗效显著，值得临床应用。
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机译：Conferenza di Consenso。 Ossigeno-Ozono Terapia Nel Trattamento Delle Lombosciatalgie da Ernia Discale Con Tecnica Iniettiva Intramuscolare paravertebrale Istituto superiore di sanita Roma 20 Novembre 2006（共识会议。腰椎椎旁肌内注射氧气 - 臭氧引起的腰椎间盘突出症.Istituto superioe di sanita。罗马，2006年11月20日）
