目的 研究心脏停跳及不停跳冠状动脉搭桥术(CABG)治疗冠心病的临床疗效.方法 纳入60例冠心病患者,随机分为接受心脏不停跳冠状动脉搭桥术的观察组(n=32)和停跳的对照组(n=28),观察比较2组治疗效果、脑利钠肽水平、心功能相关指标.结果 观察组治疗的总有效率96.9%高于对照组(82.2%),E峰、E/A值、LVEF高于对照组,A峰LVEDD低于对照组(P均<0.05);观察组治疗后6 h起BNP水平明显低于治疗前,对照组治疗后12 h起BNP水平明显低于治疗前(P均<0.05),观察组治疗后各时点BNP水平均低于对照组(P均<0.05).结论 心脏不停跳冠状动脉搭桥术后疗效更好,心功能恢复更快,具有积极的治疗意义.%Objective To study the effects between patients given on pump and off pump coronary artery bypass graft ( CABG ). Methods 60 cases of coronary heart disease patients were retrospectively studied and divided into observation group( n = 32 ) who were given off pump CABG and control group( n = 28 ) who were given on pump CABG. Then the curative effect, BNP, heart function indexes were observed. Results Total efficiency were 96. 9% in observation group which was better than in control group( 82. 2% ),E peak,E/A,LVEF were significantly higher in the observation group than control group ( all P < 0. 05 ), LVEDD were lower than control group ( P < 0.05 ); BNP levels of observation group were significantly lower 6h after treatment, BNP levels of control group were significantly lower 12h after treatmen( P <0. 05 ). Conclusion Off pump CABG has positive therapeutic significance for its better curative effect, better and faster recovery of cardiac function.
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