ObjectiveTo understand the clinical efifcacy and safety of intensity modulated radiotherapy for cervical cancer patients, and to provide reference for clinical application.Method307 cervical cancer patients treated with intensity modulated radiotherapy were selected as the research objects from June 2010 to June 2012 in our hospital, they were randomly divided into two groups. 162 patients who underwent intensity modulated radiotherapy as observation group, 145 patients who underwent conventional radiotherapy as control group. The clinical curative effects, survival time, incidence of untoward reactions were compared between the two groups.ResultThe total effective rate of observation group was 84.57% (137/162), that of control group was 83.44% (121/145), there was no signiifcant difference between the two groups (P>0.05). Follow-up for 36~60 months, there were no signiifcant differences in overall survival rate, disease free survival and local control rate of 1, 2, 3 years between the two groups (P>0.05). The incidence rate of untoward reaction in observation group was signiifcantly lower than control group (P<0.05).Conclusion Intensity modulated radiotherapy has good clinical effect and lower incidence of untoward reactions in the treatment of cervical cancer.%目的：了解适形调强放射治疗对宫颈癌患者的临床疗效及安全性，为临床应用提供参考。方法选取2010年6月至2012年6月本院收治的307例接受放射治疗的宫颈癌患者为研究对象，将其随机分为两组，观察组患者（162例）接受适形调强放射治疗，对照组患者（145例）接受常规放射治疗，比较两组患者临床疗效、生存时间、不良反应发生情况。结果观察组患者治疗总有效率为84.57%（137/162），对照组为83.44%（121/145），两组比较差异无显著性（P＞0.05）。随访36～60个月，两组患者1、2、3年的总生存率、无瘤生存率和局部控制率比较差异均无显著性（P＞0.05）。观察组患者总不良反应发生率明显低于对照组（P＜0.05）。结论适形调强放射治疗在宫颈癌患者治疗中具有较好的临床效果，且患者不良反应发生率较低。
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