ObjectiveTo explore and analyze the correlation between cardiovascular disease risk, food glycemic index and glycemic load correlation.MethodSelected 2137 cases of 50~70 years old general physical examination as the research objects in our hospital check-up from January 2007 to January 2009 by followed-up 5 years, statistical study cases complicated with cardiovascular disease, and analyzed the possible inlfuencing factors.ResultThere were medical examination of 65 cases complicated with cardiovascular disease in 2137 cases in the 5 years, through a single factor chi-square test shows that, high glycemic load, high glycemic index, obesity, smoking, drinking, and negative emotions could easily induce cardiovascular disease, after multiple Logistic regression analysis for risk factors from big to small respectively was glycemic index (OR=20.950,P=0.000), high glycemic load (OR=6.716,P=0.000), obesity (OR=2.808,P=0.000) and alcohol (OR=1.683,P=0.00).ConclusionFood glycemic index and glycemic load can be used as a blood glucose reaction after eating two important indexes, the introduction of concept of glycemic index and glycemic load food to eating healthy education can improve human glycosylated hemoglobin, blood lipid, insulin resistance and break traditional food exchange and to prevent cardiovascular complications, such as worthy of further popularization and application in clinic.%目的：探究并分析心血管疾病风险与食物血糖指数和血糖负荷的相关性。方法选取2007年1月至2009年1月2137例于本院体检的50～70岁体检者为研究对象。随访5年，统计研究对象并发心血管疾病的例数，并对可能的影响因素进行分析。结果随访结束后，2137例体检者中65例并发心血管疾病，单因素χ2检验显示：高血糖负荷、高血糖指数、肥胖、吸烟、饮酒和负性情绪等因素易诱发心血管疾病，多因素Logistic回归分析得到危险因素由大至小分别为：高血糖指数（OR＝20.950，P＝0.000）、高血糖负荷（OR＝6.716，P＝0.000）、肥胖（OR＝2.808，P＝0.000）和饮酒（OR＝1.683，P＝0.00）。结论血糖负荷和食物血糖指数可以作为进餐后血糖反应的两项重要指标，引入食物血糖指数、血糖负荷的概念对健康人群进行饮食教育能够改善人体糖化血红蛋白、血脂、胰岛素抵抗水平，具有预防心血管疾病及其并发症的作用，值得临床进一步推广应用。
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