Objectives:To study the anesthesia effect of general anesthesia and epidural anesthesia combined with intravenous anesthesia and their effect on the immunization of ovarian cancer patients.Methods:114 patients with ovarian cancer admitted in our hospital from December 2014 to December 2016 were randomly divided into general anesthesia group and combination anesthesia group,with 57 cases in each group.General anesthesia group was treated with general anesthesia,and epidural anesthesia combined with intravenous anesthesia was used in combination anesthesia group.The success rate,the degree of muscle relaxation and the immune function of the two groups were compared.Results:The success rate of obstruction was 96.49％ and 98.25％ respectively in the two groups.The satisfactory rate of muscle relaxation was 94.74％ and 96.49％ respectively,without significant difference between two groups (P ＞ 0.05).The number of T lymphocyte subsets and NK cell counts between the two groups had significant difference (P ＜ 0.05).Conclusion:The effects of general anesthesia and epidural anesthesia combined intravenous anesthesia are satisfactory.The impact of epidural anesthesia combined intravenous anesthesia on the immune function of patients is low,so it can be clinically promoted.%目的:研究全身麻醉和硬膜外麻醉复合静脉麻醉的麻醉效果及对卵巢癌患者免疫功能的影响情况.方法:以我院2014年12月至2016年12月收治的114例卵巢癌患者为研究对象,随机分为全麻组和联合组,每组各57例,全麻组采用全身麻醉,联合组采用硬膜外麻醉复合静脉麻醉.比较观察两组阻滞成功率、肌肉松弛程度满意率以及免疫功能变化情况.结果:两组患者阻碍成功率分别为96.49％和98.25％;肌肉松弛程度满意率分别为94.74％和96.49％;组间无明显差异(P＞0.05).在不同时期两组患者T淋巴细胞亚群计数及NK细胞计数差异均具有统计学意义(P＜0.05).结论:全身麻醉和硬膜外麻醉复合静脉麻醉麻醉效果均较满意,硬膜外麻醉复合静脉麻醉对患者免疫功能影响较低,可进行临床推广.
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