Objectives:To investigate the clinical value of transvaginal ultrasound in monitoring follicular development of infertile patients.Methods:From July 2011 to June 2015,69 infertile females were selected as infertility group and 69 healthy women of childbearing age in the same period as control group.Transvaginal ultrasonography was adopted to observe the changes in follicle diameter and endometrial thickness.The blood flow parameters of follicular phase and luteal phase were analyzed.Results:In infertility group,the follicle size (6.42 ± 1.72 mm) and endometrial thickness (6.23 ± 0.92 mm) of dysplasia follicle,and follicle size (11.04 ± 1.31 mm) and endometrial thickness (7.34 ± 1.02 mm) of small follicle were significantly lower than these in the control group [follicle size (21.56 ± 3.13 mm),endometrial thickness (12.12 ± 1.09 mm)] (P ＜ 0.05).The follicle phase resistance index (0.73 ± 0.15) and average blood flow velocity (20.38 ± 0.78 cm/s) of ovulation,follicular phase resistance index (0.55 ± 0.12) and average blood flow velocity (18.14 ± 1.07 cm/s) of anovulation had significant differences (P ＜ 0.05).And the luteal phase resistance index and average blood flow rate between the two groups had no significant difference (P ＞ 0.05);before the treatment,the rates of small follicle ovulation,follicular dysplasia and luteinized follicles were 18.84％,72.46％,and 8.7％,respectively,while after treatment,they were 2.9％,13.04％ and 1.45％,respectively,with significant difference between before and after treatment (P ＜ 0.05).Conclusion:Transvaginal ultrasound monitoring of follicular development,endometrial thickness,combined with ovarian artery blood flow parameters are of great value in the diagnosis and treatment of infertility.%目的:探讨经阴道超声监测卵泡发育对不孕症患者临床价值.方法:收集2011年7月至2015年6月69例不孕症女性临床资料,选取同时期健康育龄女性69例作为对照,均行阴道超声检查,观察排卵期卵泡大小和子宫内膜厚度变化,对卵泡期和黄体期的血流参数情况进行分析.结果:不孕症卵泡发育不良卵泡大小为(6.42±1.72) mm、子宫内膜厚度为(6.23±0.92) mm,小卵泡发育卵泡大小为(11.04±1.31)mm、子宫内膜厚度为(7.34±1.02) mm,对照组卵泡大小为(21.56±3.13)mm、子宫内膜厚度为(12.12±1.09) mm,对照组显著高于其他两者(P＜0.05);不孕症可排卵卵泡期阻力指数(0.73±0.15)、平均血流速度(20.38±0.78)cm/s,不孕症不排卵卵泡期阻力指数(0.55±0.12)、平均血流速度(18.14±1.07)cm/s,两者比较差异显著(P＜0.05),而两组黄体期阻力指数、平均血流速度差异则不显著(P＞0.05);治疗前小卵泡排卵、卵泡发育不良、卵泡黄素化发生率分别为18.84％、72.46％、8.7％,治疗后分别为2.9％、13.04％、1.45％,治疗前后比较差异显著(P＜0.05).结论:经阴道超声监测卵泡发育、子宫内膜厚度,结合卵巢动脉血流参数对不孕症临床诊治有重要价值.
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