ROS即reactive oxygen species,是需氧细胞在代谢过程中产生的一系列活性氧簇,包括:O2、H2 O2、O2-、-OH等.精子的一些正常的生理活动需要ROX,如获能、超活化、精卵质膜融合过程等.但过多的ROS对精子是有害的,可以通过影响精子形态、活动性、质量及功能包括DNA损害产生作用.精子正常的生理活动会产生ROS,而精索静脉曲张、糖尿病、吸烟、饮酒等因素可导致精子ROS升高,从而影响精子的质量.%Reactive oxygen species (ROS),including O2,H2O2,O2-and · OH,are a series of molecules related to aerobic metabolism.ROS plays an important role in sperm capacitation and acrosome reaction.However,overproduction of ROS has been a detrimental factor to sperm,which can influence sperm morphology,motility and DNA.The normal physical activity can generate ROS whose concentration would rise under the condition of varicocele,diabetes,smoking,and drinking.The article introduced the generation of ROS and its influence on sperm.
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