Objectives:To explore the epidemiology and the associated risk factors of recurrence in patients with condyloma acuminatum.Methods:2094 patients with condyloma acuminatum,from August 2010 to August 2014,were surveyed.The basic information had been collected to do epidemiology research of condyloma acumina-tum.The associated risk factors of recurrence were analyzed by logistic regression method.Results:Patients from 21 to 50 years old were the high morbidity of condyloma acuminatum and the morbidity was 88.40%.The morbidity of male was higher than that of the female in the same age group.The morbidity presented increase trend from 2010 to 2014,while the morbidity of the male was higher than that of the female from 2010 to 2012 and the morbidity of the female was higher than that of the male from 2012 to 2014.The sex,age,course of disease,lesion location, combined herpes progenitalis,combined urinary tract infection,positive HIV test were the associated risk factors of recurrence in patients with condyloma acuminatum.Conclusions:The high morbidity of condyloma acuminatum is from 20 to 50 years old and the increase trend of morbidity is the epidemiology.The sex,age,course of disease,le-sion location,combined herpes progenitalis,combined urinary tract infection,positive HIV test are the associated risk factors of recurrence in patients with condyloma acuminatum.%目的：探究临床尖锐湿疣的流行病学特征和复发的相关危险因素的分析。方法：分析2010年8月至2014年8月我院皮肤性病科收治的尖锐湿疣患者2094例，采集患者基本信息进行临床尖锐湿疣流行病学研究，采用 Logistic 回归方法统计分析尖锐湿疣复发的相关危险因素，以 P ＜0．05具有统计学差异。结果：流行病学研究发现21～50岁是临床尖锐湿疣的高发病年龄段，发病率为88．40％；同年龄段中男性发病率高于女性；尖锐湿疣从2010年到2014年发病率呈上升趋势；2010年至2012年间男性发病率高于女性，而2013年至2014年女性发病率高于男性。通过 Logistic 回归分析发现性别、年龄、病程、病灶位置、合并生殖器疱疹、合并尿道感染、HIV 阳性患者是尖锐湿疣复发的相关因素。结论：临床尖锐湿疣好发于20～50年龄段，临床发病率呈上升趋势；临床尖锐湿疣的复发与性别、年龄、病程、病灶位置、合并生殖器疱疹、合并尿道感染、HIV 阳性患者有关。
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