Objectives:To investigate the clinical efficacy of vaginal ultrasound monitor of follicular devel-opment in the treatment of female infertility.Method:50 patients with infertility who came to our hospital between August 2012 and August 2013 were selected as the observation group.They were treated with vaginal ultrasound mo-nitoring of follicular development.Meanwhile,50 patients who were treated with ovulation test and basal body tem-perature measurement were retrospectively analyzed and were regarded as the control group.Follicular maturation and ovulation,and the guidance of a successful pregnancy ratio after sex guidance were observed and recorded.Re-sults:Follicular development was detected in 38 patients in the control group and 30 in the observation group,and the difference of number of patients was of no statistically significance (P>0.05).The pregnancy rate of the obser-vation group (46.0%)was significantly higher than that of the control group (20.0%)(P<0.05).In the obser-vation group,follicular maturation,luteinized follicular artesian,pelvic fluid,uneven rate of endometrial thickness, daily follicular growth,follicular diameter were significantly different between those who were pregnant and those who were not pregnant (P<0.05).In the observation group,endometrial thickness of those who were pregnant was less thicker than those who were not pregnant,and the difference was statistically significant (P<0.05 ).Conclu-sion:Transvaginal ultrasound monitor of follicular development is worthy of promotion in the treatment of female in-fertility.%目的：探讨阴道超声检测卵泡发育在治疗女性不孕症中的临床疗效。方法：选择我院2012年8月至2013年8月收治的不孕患者50例作为观察组，采用阴道超声检查女性患者卵泡发育情况；同时回顾性选择我院使用引导超声前收治的通过测排卵试纸、基础体温测定治疗的不孕患者50例作为对照组。检查并记录两组不孕症患者检测卵泡成熟和排卵情况后，指导性生活后的成功受孕率。结果：对照组有38例患者卵泡发育成熟，而观察组检测到30例卵泡成熟，少于对照组，但差异无统计学意义（P＞0.05）；观察组患者的受孕率（46.0％）高于对照组（20.0％），差异有统计学意义（P＜0.05）；观察组怀孕患者的卵泡成熟、卵泡黄素化、卵泡闭锁、盆腔积液、子宫内膜厚度不均与未受孕患者间差异有统计学意义（P＜0.05）；观察组受孕患者卵泡每日增长速度和成熟时卵泡直径均大于未受孕患者，且差异有统计学意义（P＜0.05）；观察组受孕患者的子宫内膜厚度低于未受孕者，更易于着床，差异有统计学意义（P＜0.05）。结论：阴道超声检测卵泡发育能更好的治疗和指导女性不孕症患者的受孕率，值得临床推广。
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