To investigate the effect of Xuefurong capsules combined with testosterone unde-canoate on middle-aged men with late-onset hypogonadism (LOH).Methods:96 LOH patients enrolled in our hospital from March 201 1 to June 2013 were randomly divided into 2 groups,with 44 cases of testosterone undecano-ate and 52 cases of Xuefurong capsules combined with testosterone undecanoate.Results:Before treatment,TT, LH,FSH,E2,PRL,IIEF -5 score and deficiency score were no significant different (P>0.05 ).After treat-ment,TT,LH,FSH and E2 were significantly higher and PRL,IIEF-5 were significantly lower in the combined group (P<0.05 ).A lower incidence of adverse reactions was observed (P<0.05 ).Conclusion:Xuefurong cap-sules combined with testosterone undecanoate on LOH is safe and effective.%目的：考察雪芙蓉胶囊联合十一酸睾酮用于中年男性迟发性性腺功能减退症（LOH）患者的临床疗效。方法：收集2011年3月至2013年6月在我院治疗的LOH病患96例，随机分为睾酮组44例和联合组52例。睾酮组口服十一酸睾酮，联合组服用十一酸睾酮联合雪芙蓉胶囊，治疗3个月。结果：两个组别治疗前TT、LH、FSH、E2、PRL、IIEF-5评分和中医肾阳虚评分无显著差异（P＞0.05）；治疗后与睾酮组比，联合组的TT、LH、FSH和E2显著增高（P＜0.05），PRL和IIEF-5评分显著降低（P＜0.05）。不良反应发生较低（P＜0.05）。结论：雪芙蓉胶囊联合十一酸睾酮用于LOH患者安全有效。
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