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血高催乳素血症导致男性性功能障碍的诊治分析

         

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目的:分析血高催乳素血症导致的男性性功能障碍的诊断与治疗策略。方法:回顾性分析我院男科2011年至2012年收治的32名血高催乳素血症导致的男性性功能障碍患者的诊疗资料,总结血高催乳素血症导致男性性功能障碍的诊断与治疗方法。所有数据均建立Excel 2013数据库,并采取SPSS19.0的统计学软件进行数据分析,计量资料均采取t检验,分析治疗前后患者血清性激素的变化。结果:32例患者中有特发性高催乳素血症23例(71.88%)、有垂体腺瘤4例(12.50%)、有微腺瘤5例(15.63%)。有勃起功能障碍29例(90.63%)、有性欲减退32例(100.00%)、有性高潮障碍7例(21.88%)。32例患者治疗后的血清催乳素含量明显低于治疗前,差异具有统计学意义(P<0.01)。32例患者治疗后的黄体生成素、卵泡刺激素以及睾酮水平均要明显高于治疗前,差异具有统计学意义(P<0.01)。经治疗后32例患者的勃起功能障碍、性欲减退以及高潮障碍等症状均有所改善。结论:高催乳素血症导致的男性性功能障碍经过病史采集、临床特征、勃起功能指数测定、体格检查、激素测定以及垂体的影像学检查可明确诊断,甲磺酸溴隐亭与十一酸睾酮的治疗效果较好,值得临床推广。%Objectives:To analyze the diagnostic and therapeutic strategies of male sexual dysfunction caused by hyperprolactinemia.Methods:A retrospective analysis of the data of 32 male subjects with sexual dys-function caused by hyperprolactinemia treated in our hospital from 201 1 to 2012 was conducted to summarize the di-agnostic and therapeutic methods of male sexual dysfunction caused by hyperprolactinemia.All data were put into Excell2013 database and statistical software SPSS19.0 was used for data analysis;measurement data were taken t test to analyze the changes of serum sex hormones before and after treatment.Results:1 )There were 23 cases (71.88%)of idiopathic hyperprolactinemia,4 cases (12.50%)of micro adenoma and 5 cases (15.63%)of pitu-itary adenoma among the 32 patients.There were 29 cases (90.63%) of erectile dysfunction,32 cases (100.00%)of decreased libido and 7 cases (21.88%)of orgasmic disorder among the 32 patients.2)The serum prolactin levels of 32 patients after treatment were significantly lower than that before the treatment,with statistically significant difference (P<0.01);The levels of luteinizing hormone,follicle-stimulating hormone and testosterone of 32 patients after treatment were significantly higher than those before the treatment,with statistically significant difference (P<0.01).3)After treatment,the erectile dysfunction,decreased libido,orgasmic dysfunction and other symptoms of 32 patients were improved.Conclusion:Male sexual dysfunction caused by hyperprolactinemia can be confirmed through history taking,clinical characteristics,erectile function index determination,physical ex-amination,hormonal measurement and imaging of pituitary.The efficacy of Bromocriptine Mesylate and testosterone undecanoate is better and worthy of promotion.

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