目的:探究慢性肾衰竭不同分期对性功能的影响.方法:选取我院于2008年12月至2010年10月收治的慢性肾衰竭患者82例,按照其病理分期进行分组探究,对激素水平、神经功能、并发症及心理状况进行对比,探讨慢性肾衰竭不同分期对性功能的影响.结果:代偿期患者促卵泡素、泌乳素及促黄体素均高于正常人群,且随着患者临床分期的加重,患者激素水平不断提高,女性提高程度较男性更为严重；代偿期患者出现3例(15.8％)神经障碍,失代偿期出现5例(21.7％),肾衰竭期出现8例(29.6％),尿毒症期出现11例(84.6％),随着患者临床分期的加重患者出现神经障碍比例不断提高；随着患者临床分期加重其并发症率不断上升,组间比较存在明显统计学差异；代偿期患者平均SCL-90得分为(157.6±51.2)分,失代偿期患者为(167.2±49.5)分,肾衰竭期为(185.0±58.7)分,尿毒症期为(193.6±59.1)分,均高于国内常模且随临床分期加重SCL-90得分显著上升,显示其心理状态不断下降.结论:随着慢性肾衰竭临床分期的加重,患者体内激素水平上升、并发症发生率不断提高,且神经系统障碍及心理障碍的程度不断加重,导致其性功能显著下降,因此,应在提供治疗的前提下加强心理治疗,帮助其恢复性功能.%Objectives:To explore the influence of different stages of chronic renal failure on sexual function.Methods:We selected 82 patients with chronic renal failure who were registered in our hospital from December 2008 to October 2010.They were grouped based on their pathological condition and were compared in terms of hormone levels,neural function,complications and psychological condition.Results:Patients in compensation stage showed higher level of FSH,prolactin and luteinizing hormone than the normal group.The severe the patients' pathological condition is,the higher level patients' hormone is.Neurological disorders appeared in 3 (15.8％) decompensated patients,in 5 decompensated patients (21.7％),and in 8 (29.6％) renal failure patients and in 11 uremia patients (84.6％).With the aggravation of patients' disease,the risk of neurological disorders increased and the complication rate accordingly rises.There existed significant differences between groups.The mean SCL-90scores were (157.6 ± 51.2) in compensated patients,(167.2 ± 49.5) in decompensated patients,(185 ± 58.7) in renal failure stage,and (193.6 ± 59.1) in uremia stage respectively.All the scores were higher than the national norm.Conclusion:With the development of chronic renal failure in patients,there is significant increase in hormone levels,the complication rate,risk of nervous system disorders and psychological disorder,causing declined sexual function.Therefore,psychological care should be provided to help the patients resume their sexual functions.
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