目的:分析并比较单纯西药合并腔道介入治疗以及中西医结合合并腔道介入治疗对男性少精弱精伴有解脲支原体感染及慢性前列腺炎引起男性不育症治疗的效果.方法:从2008年7月至2011年12月对56例男性少精弱精伴有解脲支原体感染及慢性前列腺炎的患者中随机分为两组(对照组与治疗组).对照组(28例)用阿奇霉素0.5g/d+左氧氟沙星0.4g/d静滴1周,再口服1周(若对阿奇霉素及左氧氟沙星耐药可改用每天米诺环素0.1g/次,Bid及司帕沙星0.3g/次,Qd,口服2周),同时运用ZRL-II-A型前列腺腔道介入治疗仪,进行尿道的腔道介入治疗3～5次(每次间隔2d),2周复查Uu转阴后开始服用VitE软胶囊100mg/次,Tid,连用3个月.治疗组(28例)在上述治疗2周后的基础上用VitE软胶囊100mg/次,Tid,加中药赞育丹汤剂加减治疗3个月.观察两组治疗前、后的精液质量指标(精液量、精子密度、活动力、存活率)的变化.结果:两组治疗前与治疗后检查分析精液,示治疗后精液质量均改善,但治疗组精液各项参数明显较对照组要高,差异有显著意义(P＜0.01).结论:对男性少精弱精伴有解脲支原体感染及慢性前列腺炎而引起男性不育症的患者,运用中西医结合合并腔道介入治疗,患者精液质量明显改善,且明显优于单纯西药合并腔道介入治疗.%Objectives:To analyze and compare the treatment effects of western medicine combined with cavitary interventional therapy and the treatment effects of integrated traditional Chinese and Western medicine combined with cavitary interventional therapy in patients with oligoasthenospermia,ureaplasma urealyticum infection and chronic prostatitis.Method:From July 2008 to December 2011,56 patients with oligoasthenospermia,ureaplasma urealyticum infection and chronic prostatitis were randomly divided into two groups.Treatment measures for twenty-eight patients in the control group included intravenous drip of azithromycin 0.5g / day and levofloxacin 0.4g / day for one week,oral treatment for the following week and the treatment of ZRL -Ⅱ-A.After two weeks,if Uu was negative,they took VitE soft capsules 100mg/time,Tid,for three months.Treatment measures for twenty-eight patients in the treatment group included 3-month Zanyudan Decoction in addition to all the above.We observed the changes of the semen quality indexes (including semen volume,sperm density,motility,survival rate) of the two groups before and after the treatment.Results:Sperm quality improved after the treatment in both groups.All indexes in the treatment group were significantly higher than those of the control group (P ＜ 0.01).Conclusion:For patients with male infertility caused by oligoasthenospermia complicated with Ureaplasma urealyticum infection and chronic prostatitis,using combination of cavitary interventional therapy,traditional Chinese medicine and Western medicine can improve sperm quality,and is better than mere western medicine combined with cavitary interventional therapy.
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