目的：分析某院短期内神经外科多例患者手术部位感染（SSI）的可能原因。方法收集该院2013年2月1日-3月15日135例神经外科手术患者资料，采用病例对照研究，回顾性分析可能引起 SSI 的危险因素。结果135例手术患者，5例发生 SSI，感染率为3．70％。病例对照研究显示，第5手术间使用情况和进行二次手术的比值比分别为4．07（95％CI ：0．52～36．65）、18．00（95％CI ：2．00～180．00）。各手术主刀医生施行手术患者 SSI率与该科2012年平均 SSI 率2．54％（17/669）比较，差异均无统计学意义（均 P ＞0．05）。第5手术间环境卫生学检测，除麻醉机袖带的菌落总数超标外，其余采样部位单位面积菌落总数均符合国家要求；且麻醉机袖带采样培养的微生物为凝固酶阴性葡萄球菌，与感染患者致病微生物无关。结论进行二次手术是此次短期多例神经外科患者发生 SSI 的高危因素。%Objective To investigate the possible causes of surgical site infection(SSI)in neurosurgical patients in a hospital during a short period of time.Methods Medical data of 135 neurosurgical operative patients from February 1 to March 15,2013 were reviewed,the possible risk factors for SSI were analyzed retrospectively with case-control study.Results Of 135 operative neurosurgical patients,5 (3.70%)developed SSI.Case-control study showed that the ratio of the run of the fifth operating room and undergoing of secondary operation was 4.07 (95%CI :0.52 -36.65)and 18.00(95%CI :2.00 -180.00)respectively.The difference between each surgeon special SSI rate and the average SSI rate in 2012 (2.54%[17/669])was not significantly different (P >0.05).Bacterial detection of en-vironmental specimens of the fifth operating room showed that except anesthetic cuff exceeded standard,the others were met the national requirements,and the isolated bacteria from anesthetic cuff was coagulase negative Staphylo-coccus ,which was not related with pathogens in infection.Conclusion “The secondary surgery”is the key risk fac-tor for SSI of neurosurgical patients.
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