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不同炮制方法对女贞子化学成分的影响

         

摘要

Objective To investigate the effects of different methods of preparation on the contents of nuzhenide and oleanolic acid in Ligustri Lucidi Fructus. Methods The same batch of Ligustri Lucidi Fructus was under preparation and process. RP-HPLC was used to determine the contents of nuzhenide and oleanolic acid in crude samples, wine-prepared samples, vinegar-prepared samples, and salt-prepared samples. Results The contents of nuzhenide were in the order as follow:salt-prepared samples (1.997 5%)>crude samples (1.600 7%)>wine-prepared samples (1.144 6%)>vinegar-prepared samples (0.894 6%). The contents of oleanolic acid were in the order as follow:wine-prepared samples (1.120 2%)>salt-prepared samples (0.924 6%)>vinegar-prepared samples (0.913 2%)>crude samples (0.899 8%). Conclusion Different methods of preparation have certain effects on the contents of nuzhenide and oleanolic acid in Ligustri Lucidi Fructus.%目的:考察不同炮制方法对女贞子主要化学成分特女贞苷和齐墩果酸含量的影响。方法用同一批次女贞子进行炮制加工,采用反相高效液相色谱法,对女贞子生品、酒制女贞子、醋制女贞子和盐制女贞子中的特女贞苷和齐墩果酸进行含量测定。结果女贞子生品及3种不同炮制品中特女贞苷含量依次为盐制女贞子(1.9975%)>女贞子生品(1.6007%)>酒制女贞子(1.1446%)>醋制女贞子(0.8946%)。女贞子生品及3种不同炮制品中齐墩果酸含量依次为酒制女贞子(1.1202%)>盐制女贞子(0.9246%)>醋制女贞子(0.9132%)>女贞子生品(0.8998%)。结论女贞子不同炮制方法对其特女贞苷和齐墩果酸的含量有一定影响。

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