目的 观察舒利迭(沙美特罗/氟替卡松干粉)联合十味龙胆花颗粒治疗支气管哮喘慢性持续期的临床疗效.方法 将110例支气管哮喘慢性持续期患者随机分为治疗组和对照组各55例,均吸入舒利迭50/250μg,早晚各1次,作为基础治疗.治疗组联合口服十味龙胆花颗粒,每次1包,每日3次.对照组联合口服复方甲氧那明胶囊,每次2粒,每日3次.连续治疗7 d.观察2组患者临床症状、体征与6 min步行距离变化.结果 治疗后,治疗组和对照组临床症状、体征均好转(P<0.05),6 min步行距离均增加(P<0.05),组间比较差异无统计学意义(P>0.05).结论 舒利迭吸入联合十味龙胆花颗粒口服短期治疗可改善支气管哮喘慢性持续期临床症状、体征与6 min步行距离,且短期疗效与舒利迭吸入联合复方甲氧那明胶囊口服无明显差异.%Objective To observe the clinical efficacy of Seretide combined withShiwei Longdanhua Granule in the treatment of chronic asthma duration.Methods Totally 110 patients with chronic asthma duration were randomly divided into treatment group and control group, 55 cases in each group. They inhaled Seretide 50/250μg, once in morning and evening, as a basic treatment. The treatment group was treated combined with oralShiwei Longdanhua Granule, 1 package each time, 3 times a day. The control group was treated combined with oral compound Methoxyphenamine, 2 capsules each time, 3 times a day. The course lasted for 7 days. The clinical symptoms, physical signs and the distance of 6-minute walk of the two groups were observed. Results After treatment, the clinical symptoms, physical signs and the distance of 6-minute walk of the two groups improved, without statistical significance between the two groups (P>0.05). Conclusion Inhaled Seretide combined with oralShiwei Longdanhua Granule for short period can improve the clinical syndromes and the distance of 6-minute walk, without statistical significance with Seretide combined with oral Methoxyphenamine.
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