目的：探讨国医大师颜正华教授处方用药规律。方法在收集颜正华教授含茯苓处方的基础上，利用中医传承辅助系统构建数据库，使用软件的统计报表模块、数据分析模块，采用关联规则、apriori算法等数据挖掘方法，分析含茯苓处方中单味药物频次、药物组合频次、关联规则与核心药物组合等。结果含茯苓处方常用于治疗眩晕、胃痛、泄泻等病证，高频药物包括陈皮、赤芍、丹参、炒酸枣仁、首乌藤等，高频药物组合包括“陈皮，茯苓”、“丹参，茯苓”、“茯苓，炒酸枣仁”等，置信度≥0.9的关联规则包括“龙骨→牡蛎”、“茯苓，龙骨→牡蛎”、“牡蛎，首乌藤→龙骨”、“炒白术→茯苓”等。结论颜正华教授含茯苓处方所用药物多具理气、安神、凉血等功效，用药较为集中，组方法度清晰。%Objective To explore the medication rules of state medical master Yan Zhenghua from the prescriptions. Methods After analyzed by the statistical report module and the data analysis module, the method of data-mining that including association rules and apriori algorithm was used to analyze the frequency of Poria and drug combination, the association rules between drugs and core drug combinations in Pro. Yan’s prescriptions via a database based on Traditional Chinese Medicine (TCM) inheritance assist system. Results The prescriptions containing Poria were commonly used to treat vertigo, stomachache, diarrhea and other syndromes. The highest frequently used drugs were Pericarpium Citri Reticulatae, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Parched Semen Ziziphi Spinosae, and Caulis Polygoni Multiflori. The most frequently used drug combinations were “Pericarpium Citri Reticulatae, Poria”, “Radix Salviae Miltiorrhizae, Poria”, and“Poria, Parched Semen Ziziphi Spinosae”. The drug association rules that the confidence coefficient was more than 0.9 were “Carina→Oyster”, “Poria, Carina→Oyster”,“Oyster, Caulis Polygoni Multiflori→Carina”, and“Rhizoma Atractylodis Macrocephalae→Poria”. Conclusion The drugs in the prescriptions containing Poria that built by Pro. Yan mostly had the effects of regulating the flow of qi, relieving uneasiness of body and mind, and cooling the blood, which reflected the clearly thought when Pro. Yan made the prescriptions.
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