Objective To explore the value of ultrafast imaging technique in evaluation of carotid stiffness in patients with chronic obstructive pulmonary disease (COPD).Methods Totally 48 COPD patients (COPD group) and 45 volunteers (control group) underwent carotid ultrasonography and ultrasound ultrafast imaging for measuring pulse wave velocity (ufPWV) of carotid artery,including beginning of the systole (PWV-BS) and end of the systole (PWV-ES).The statistical analysis was performed.Results Compared with control group,PWV-BS and PWV-ES increased in COPD group (both P＜0.05).ufPWV of COPD patients had negative correlation with the force expiratory volume in 1 s (PWV-BS:r=-0.40,P＜0.01;PWV-ES:r=-0.41,P＜0.01).Conclusion Ultrafast imaging technique can be used to evaluate carotid arteries;Stiffness in patients with COPD,providing important basis for clinical treatment and prognosis evaluation.%目的 探讨极速成像技术评价慢性阻塞性肺疾病(COPD)患者颈动脉僵硬度的价值.方法 48例COPD患者(COPD组)和45名志愿者(对照组)接受常规颈动脉超声检查后,应用超声极速成像技术测量颈总动脉脉搏波传导速度(ufPWV),包括收缩期起始时PWV值(PWV-BS)及收缩期结束时PWV值(PWV-ES),并进行统计学分析.结果 与对照组比较,COPD组PWV-BS值和PWV-ES值均升高(P＜0.05);COPD患者ufPWV值与第1秒用力呼气容积呈负相关(PWV-BS:r=-0.40,P＜0.01;PWV-ES:r=-0.41,P＜0.01).结论 极速成像技术可早期评价慢性阻塞性肺疾病患者颈动脉硬化,为临床治疗方案的选择及预后评价提供重要依据.
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