Objective To explore the value of cardiovascular magnetic resonance feature tracking (CMR-FT) in quantita tive evaluation of myocardium deformation in patients with hypertrophic cardiomyopathy (HCM).Methods Sixteen HCM patients (HCM group) and 18 healthy volunteers (control group) were enrolled and measured with CMR-FT.The differences of left ventricular (LV) end diastolic volume (LVEDV),LV end systolic volume (LVESV),LV ejection fraction (LVEF),left ventricular mass (LVMASS) and LV global radial strain (RS),LV global circumferential strain (CS) were compared between the two groups.The correlations between segmental wall thickness and segmental RS and CS were studied.And the correlation among global RS,CS and LVEDV,LVESV,LVEF,LVMASS were analyzed.Results LVMASS in HCM group was higher than that in control group ([133.74±79.13]g vs [76.87±14.15]g,P=0.01).No sig nificant differences of LVEDV,LVESV,LVEF were found between HCM group and control group (all P＞0.05).Global RS and CS were significantly lower in HCM group than those in control group (RS:[27.05 ± 13.35]％ vs [40.62 ± 4.92] ％,P＜0.01;CS:[-8.68± 5.56] ％ vs [-20.73 ± 1.56] ％,P＜0.01).No significant correlations was observed between segmental wall thickness and segmental RS (r=-0.41,P＜0.01),CS (r=0.28,P＜0.01),respectively.In HCM group,no significant correlations was observed between global RS (r=-0.36,-0.41,0.22,-0.36),CS (r=0.34,0.10,0.22,0.42) and LVEDV,LVESV,LVEF,LVMASS,respectively (all P＞0.05).Conclusion CMR-FT is conducive to quantitative evaluate myocardial deformation in HCM patients.%目的 探讨心脏磁共振(CMR)特征追踪(CMR-FT)技术定量评价肥厚型心肌病(HCM)患者心肌形变的价值.方法 对16例HCM患者(HCM组)及18名健康志愿者(正常对照组)采用CMR-FT技术行CMR检查.比较两组间左心室舒张末期容积(LVEDV)、收缩末期容积(LVESV)、左心室射血分数(LVEF)、左心室质量(LVMASS)及左心室心肌整体径向应变(RS)、环向应变(CS)的差异.并分析HCM患者各节段室壁厚度与节段性RS、CS的相关性及整体RS、CS与LVEDV、LVESV、LVEF、LVMASS间的相关性.结果 HCM组的LVMASS高于正常对照组[(133.74±79.13)g vs (76.87±14.15)g,P=0.01].两组间LVEDV、LVESV、LVEF差异均无统计学意义(P均＞0.05). HCM组心肌整体RS、CS值均明显低于正常对照组[RS:(27.05±13.35)％ vs (40.62±4.92) ％,P＜0.01;CS:(-8.68±5.56)％vs(20.73±1.56)％,P＜0.01]. HCM患者各节段室壁厚度与节段性RS(r=-0.41,P＜0.01)、CS(r=0.28,P＜0.01)间无相关性;心肌整体RS(r=0.36、-0.41、0.22、-0.36) 、CS(r=0.34、0.10、0.22、0.42)与LVEDV、LVESV、LVEF、LVMASS间无相关性(P均＞0.05).结论 CMR-FT有助于定量评估HCM患者心肌形变情况.
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