Some researches have found out, in recent years, there usually exist calcium negative equilibrium and urinary calcium elevation in diabetes mellitus due to glucose metabolic disturbance.(1,2) On the other hand, sex hormone reduction is apparently concerned with Kidney deficiency, with worsened bone mineral substance loss resulting from Kidney Deficiency that resulted in postmenopausal osteoporosis.(3,4) Diabetes in middle aged and elderly comes on when the women patients are in the menopausal or postmenopausal state, so the deterioration of the ovary endocrine function and the reduction of the serum estradiol level will become more remarkable, and Kidney Deficiency as well as calcium negative equilibrium will also become more obvious. For this reason, a study has been conducted on the treatment effect of combining medicinal herbs and glibenclamide in middle aged and elderly female diabetic patients.
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