Decompressive craniectomy for malignant middle cerebral artery infarctions: a meta-analysis

Long Xu; Te Lu; Xiaogang Tao; Dandan Wang; Weiming Liu; Jingsheng Li; Baiyun Liu

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Decompressive craniectomy for malignant middle cerebral artery infarctions: a meta-analysis

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Background: Decompressive craniectomy (DC) has been the classical management for malignant middle cerebral artery infarctions (mMCAI) in clinical practice. However, the association between DC and mMCAI remains unclear. This review went to evaluate the efficacy of DC in treating mMCAI patients. Methods: Studies were entirely searched since the foundation dates of multiple databases to June 2016. All major databases were involved, including Cochrane Central Register of Controlled Trials, EMBASE, MEDLINE, and other sources. the bias risk of studies involved were evaluated. Modified Rankin Scale was defined as Primary outcome, Odds Ratio and 95% confidence intervals was taken as measurements. T2 (tau-squared) test, I2 test, and chi-square tests were used for statistical heterogeneity evaluation for each meta-analysis result, followed by fixed-effect model. Mantel-haenszel method was used in the process of summary estimations. All of the meta-analysis was conducted by Review Manager 5.3.Results & Conclusion: One thousand one hundred forty-five records of data were critically identified and collected through databases and 14 studies were finally involved. Result suggested that DC can ameliorate the suboptimal outcome of mMCAI patients.

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《中华神经外科杂志（英文）》 |2017年第003期|142-149|共8页
作者
Long Xu; Te Lu; Xiaogang Tao; Dandan Wang; Weiming Liu; Jingsheng Li; Baiyun Liu;
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Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 6 Tiantan Xili, Dongcheng District, Beijing 100050, People's Republic of China;

China National Clinical Research Center for Neurological Diseases (NCRC-ND), Beijing 100050, China;

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 6 Tiantan Xili, Dongcheng District, Beijing 100050, People's Republic of China;

China National Clinical Research Center for Neurological Diseases (NCRC-ND), Beijing 100050, China;

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 6 Tiantan Xili, Dongcheng District, Beijing 100050, People's Republic of China;

China National Clinical Research Center for Neurological Diseases (NCRC-ND), Beijing 100050, China;

China National Clinical Research Center for Neurological Diseases (NCRC-ND), Beijing 100050, China;

Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, 6 Tiantan Xili, Beijing 100050, China;

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 6 Tiantan Xili, Dongcheng District, Beijing 100050, People's Republic of China;

China National Clinical Research Center for Neurological Diseases (NCRC-ND), Beijing 100050, China;

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 6 Tiantan Xili, Dongcheng District, Beijing 100050, People's Republic of China;

China National Clinical Research Center for Neurological Diseases (NCRC-ND), Beijing 100050, China;

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 6 Tiantan Xili, Dongcheng District, Beijing 100050, People's Republic of China;

China National Clinical Research Center for Neurological Diseases (NCRC-ND), Beijing 100050, China;

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Decompressive craniectomy for malignant middle cerebral artery infarctions: a meta-analysis

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