Objective The effects and complications of two anesthetic methods for endoscopic nasal pituitary tumor resection were discussed.Methods A total of 52 American Society of Anesthesiologists (ASA) Ⅰ ～ Ⅱ cases who performed endoscopic nasal pituitary tumor resection were enrolled into the study.Under the monitoring of Narcotrend,Sevoflurane-remifentanil anesthesia (Group S) and Propofol target controlled infusion (TCI)-remifentanil anesthesia method (Group P) were used in the cases randomly.The changes of mean arterial pressure (MAP) and heart rate (HR) were observed,and the time of opening eyes and post-operative complications were recorded.Results There was no significant difference in mean arterial pressure,heart rate,the opening eyes and the post-operative complications between two groups (P ＞0.05).There was significant difference in mean arterial pressure and heart rate between two groups (P ＜0.05).Conclusion Two anesthetic techniques can be used safely in the neurosurgery operation,and the intra-operative hemodynamic is stable and the recovery is rapid.%目的 观察比较两种麻醉方法在经鼻内镜下垂体瘤切除术的麻醉效果和并发症.方法 选择美国麻醉医师协会(ASA)分级Ⅰ～Ⅱ级择期行经鼻内镜下垂体瘤切除术的患者52例,在Narcatrend监测下,随机接受七氟醚-瑞芬太尼麻醉(S组)和丙泊酚靶控输注(TCI)-瑞芬太尼麻醉(P组),观察平均动脉压(MAP)和心率(HR)的变化,记录睁眼时间和术后并发症.结果 组间比较两组患者的MAP和HR无显著性差异(P＞0.05);组内比较MAP和HR差异有统计学意义(P＜0.05);睁眼时间和术后并发症均无统计学差异(P＞0.05).结论 两种麻醉方法都可以安全应用于此类神经外科手术,术中血流动力学稳定且患者苏醒迅速.
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