Objective To study the agreement of quantitative measurement and Genant semi-quantitative assessment in DXA image for the evaluation of vertebral fractures.Methods BMD measurements of proximal femur and X-ray scan of T4-L5 were consecutively performed in 217 postmenopausal women aged over 50 years old.The vertebral fractures were identified by quantitative measurement and Genant semi-quantitative assessment,respectively.The reproducibility of vertebral fractures identified by two methods was estimated.The clinical characteristics with or without vertebral fractures was compared.Results Fifty-nine patients with vertebral fracture (27.19％) were identified by quantitative measurement and 60 patients with vertebral fracture (27.65％) were identified by Genant semi-quantitative assessment.The k of reproducibility between quantitative measurement and Genant semi-quantitative assessment was 0.80.No difference of the characteristics of women with or without vertebral fractures was found.Conclusion Both Genant semi-quantitative assessment and quantitative measurement are effective methods for evaluating vertebral fractures.%目的 比较形态学定量评估方法和Genant半定量方法对DXA影像进行椎体骨折评估的一致性.方法 对217例≥50岁绝经后女性作骨密度检测的同时进行胸腰椎T4～L5正侧位扫描,采用形态学定量评估方法和Genant半定量方法进行椎体骨折评估,比较二种方法确定椎体骨折的一致性和二种方法确定椎体骨折组与无椎体骨折组的临床特征.结果 形态学定量评估方法确定59例椎体骨折,椎体骨折率为27.19％;Genant半定量方法确定60例椎体骨折,椎体骨折率为27.65％.kappa一致性分析,κ=0.80.二种方法确定椎体骨折组与无椎体骨折组的临床特征无统计学差异.结论 Genant半定量方法和形态学定量评估方法均是评估椎体骨折的有效方法.
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