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首页> 中文期刊> 《中国耳鼻咽喉颅底外科杂志》 >催乳素垂体腺瘤经蝶显微外科治疗

催乳素垂体腺瘤经蝶显微外科治疗

         
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目的探讨催乳素垂体腺瘤经蝶显微手术的治疗效果。方法总结119例催乳素垂体腺瘤采取经蝶显微手术治疗的安全性与远期疗效。本组女107例，男12例。年龄13～56(平均36.7)岁。术前均经CT扫描或MRI确诊，其中大腺瘤15例(12.61%)，微腺瘤104例(87.4%)。手术采取经唇下-鼻中隔-蝶窦入路或经鼻前庭-鼻中隔-蝶窦入路行肿瘤切除术。结果术后并发症少，无死亡。103例(86.6%)行随访观察，随访期6月～7.5年(平均3.5年)，88例(85.4%)获治愈效果。结论采用经蝶显微手术切除本型肿瘤是一种安全、有效的治疗方法。%Objective　To probe the curative effect on prolactin-secreting pituitary adenoma (PRL-SPA). Methods　The long-term efficacy and safety of transsphenoidal microsurgical resection for 119 patients with PRL-SPA were reviewed at our department of neurosurgery. There were 107 females and 12 males. The patients ranged in age from 13 to 56 years with a mean of 36.7 years. Preoperative diagnosis was made by CT or MRI scan. Of the patients, 15 (12.6%) were macroadenomas and 104 (87.4%) were microadenomas. Operations were performed via either the sublabio-septo-sphenoidal approach or the naso-vestibulo-sphenoidal approach. Results　Operative morbidity was low and there was no operative mortality in this group. Long-term follow-up review ranging from 6 months to 7.5 years (mean 3.5 years) in 103 (86.6%) patients revealed a cure of 88 patients (85.4%). Conclusion　The microsurgical technique via transsphenoidal approach to remove PRL-SPA is a safe and effective method.

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