目的:对脑卒中和轻中型颅脑损伤的失语症患者行进高压氧治疗,探讨高压氧对失语症患者语言功能的影响及康复机制.方法:将40例失语症患者按入组次序分为治疗组和对照组.治疗组在常规治疗的基础上于发病7d后进行高压氧治疗,15d1个疗程,疗程之间休息3d,共3个疗程,运用语言障碍诊治仪ZM2.1检测每一疗程患者的语言功能并与对照组比较,观察语言功能的变化.结果:治疗组与对照组各疗程疗效比较:第一疗程后各项语言功能均有所提高,但与对照组比较差异无统计学意义(P＞0.05);第二疗程后,除听读字亚项外,治疗组10个亚项语言功能明显高于对照组(P＜0.05),第三疗程后11个亚项语言功能均明显高于对照组(P＜0.05).治疗组各疗程前后疗效比较:每1疗程结束后各项语言水平均有提高,其中第一、第二疗程后复杂指令、表达语音和表达语义3个亚项明显改善(P＜0.05).结论:高压氧可能通过促进神经细胞的功能恢复和自我修复,减轻脑缺血再灌注,从而促进失语症患者语言功能的康复,这种作用在第一及第二疗程表现最佳,其康复作用表现为加快其原有恢复的速度,并不针对于某些语言功能.%AIM: To explore the effects of hyperbaric oxygen (HBO) therapy on language function of aphasics and it's mechanisms. METHODS: Forty patients with aphasics after mild and moderate cerebral trauma and stroke were chosen and divided into therapy group (20 patients) and control group (20 patients). All the patients in both groups received routine therapy.Besides routine therapy, patients in therapy group also received HBO therapy. The HBO treatment contained three courses, each lasts for 15 days at an interval of 3 days. The language functions ( including 11 sub - items) were tested with the Apparatus ZM2.1for Diagnosis and Treatmern of Language Disorders (Language Disorders ZM2.1) before and after each course of HBO and be compared between the two groups. RESULTS: The therapeutic effects between the therapy group and the control group: the scores of 10 sub- items are significantly higher than those of the control group after the 2nd course (P＜0. 05); After the 3rd course, all 11 sub - items were improved significantly ( P ＜ 0.05). The therapeutic effects before and after each course of the therapy group:the scores of the advanced dictation, voice expression and semantic expression increased significantly after the 1st and the 2nd course ( P ＜ 0.05). CONCLUSIONS: The HBO therapy might facilitate the recovery of the language function of the aphasics by promoting the recovery and the self- reparation of the neurocytes and alleviating the focal ischemia - reperfusion. The result of this effect would facilitate the original recovery velocity and not be focused on some language functions and much more obvious in the 1st and the 2nd course.
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