Five natriuretic peptides (NP) have been identified: A- type, B- type, C- type, D-type and V - type. AU of them have tinged- structures. The actions of the natriuretic peptides are modulated through their cognate receptors, which are named as NPR- A, NPR- B and NPR- C. The receptors are in-volved in the cGMP- dependent signaling cascades, which take part in many different physiological regulation,such as diureses, vasedilatation, depressing blood pressure, improving immunity, promoting development of bone, regulating nerve system and so on. At present, AhT and BNP have become a marker in diagnostic some cardiovascular diseases.
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