首页> 中文期刊> 《中国实用妇科与产科杂志》 >输卵管切除术对体外受精-胚胎移植中控制性超促排卵的影响

输卵管切除术对体外受精-胚胎移植中控制性超促排卵的影响

         

摘要

Objective To investigate the effect of salpingectomy on the function of ovary in patients undergoing an rnIVF - ET treatment cycle. Methods The ovarian response to superovulation were evaluated in patients who previously rnhad undergone unilateral salpingectomy because of ectopic pregnancy(study group)and patients with unexplained infertilrnity with intact salpinx served as controls. Results There were no differences in the total numbers of follicles,oocytes rerntrived from both ovaries and the cycle characteristics between study and control groups. Among the patients who had unrndergone salpingectomy, significantly fewer follicles developed and consequently fewer oocytes were retrieved from the ornvary on the operated side( P < 0.01, P < 0.05 ). Conclusion Salpingectomy has no effect on ovarian volume in short pernriod, but has detrimental effect on ipsilateral ovarian function. So the salpingectomy can not be performed in patients unrndergoing IVF - ET in whom the other ovary has already been damaged or missing. We should try our best to reserve the rnsalpinx during tubal pregnancy if the patients need to keep their reproductive capabilities.%目的探讨输卵管切除后对卵巢功能的影响。方法选择因异位妊娠行一侧输卵管切除的患者手术rn侧卵巢与对侧卵巢及行输卵管切除的患者与双侧输卵管健全的患者,在行体外受精-胚胎移植(IVF-ET)中其rn卵巢对控制性超促排卵的反应。结果输卵管切除侧卵巢尽管其体积无明显改变,但其卵泡数及所获卵子数明rn显少于健侧卵巢。而存留一侧输卵管患者与对照组相比,在卵巢大小、用药量、用药天数、子宫内膜厚度、卵泡数rn及所获卵子数上并无显著差别。结论输卵管切除术在短期内虽然不能影响卵巢的体积,但却降低了同侧卵巢rn的储备功能。因此,临床上对有生育要求的异位妊娠患者,应尽可能地保留患侧输卵管。对于输卵管积水行体外rn受精-胚胎移植者,如对侧卵巢缺如或卵巢功能低下,不宜做预防性输卵管切除术。

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