Circumferential esophageal mucosal lesions were relatively rare and they were more difficult to be treated endoscopically.Endoscopic resection (ER) has a high success rate for short segment mucosal lesions.Endoscopic submucosal dissection (ESD) was developed for en bloc removal of large mucosal lesions,but endoscopic submucosal tunnel dissection (ESTD) is a safe and effective alternative for long segment circumferential esophageal superficial neoplasms with a higher operation speed in contrast with ESD.Postoperative stricture after circumferential mucosal resection was inevitable and steroid therapy,balloon dilation and covered esophageal stent placement were recommended in the prevention of post-endoscopic therapy strictures.%食管环周病变较少见,内镜下治疗相对困难.内镜下切除术(ER)可用于治疗短段环周病变.内镜黏膜下剥离术(ESD)可完整切除病变,适用于范围较大的病变,但对于长环周病变的切除仍较为困难.内镜下隧道式黏膜剥离术(ESTD)可提高食管环周病变的切除速度,且病变长度不再成为食管黏膜病变内镜下治疗的限制.环周黏膜病变切除后狭窄不可避免,推荐术后预防性应用激素、球囊扩张或支架置入,可能需要联合多种治疗手段.
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