Objective To summarize the surgical treatment effect on patients who suffered from multiple cerebral cavernous malformations and epilepsy.Methods The data of 15 patients who underwent operation for multiple cerebral cavernou malformations and epilepsy were retrospectively analyzed.Results After operation,13 patients had no seizures from operation finished to follow-up and 2 patients experienced epilepsy recurrence after operation.One patient appeared the muscle force of contralateral limbs decreasing after the resection of cavernous malformation in the frontal lobe,and then was gradually rehabilitated after treatment.No patient died after the operation.During the follow-up period of 27.5 months on average (6-66 months),no patient had a recurrence of cavernous malformations.Conclusions Patients with cerebral multiple cavernous malformations are prone to be complicated by epilepsy.According to the location of the cavernous malformation and intraoperative electrophysiological monitoring,we can effectively treat the multiple cerebral cavernous malformations complicated by epilepsy by individualized epileptogenic lesion resection,cortical thermal ablation and enlarged resection of the hippocampus amygdala.%目的 总结脑多发海绵状血管畸形并发癫痫患者的手术治疗效果.方法 回顾性分析15例脑多发海绵状血管畸形并发癫痫手术治疗患者的病例资料.结果 手术治疗后,13例患者手术后至随访时无癫痫发作,2例患者术后再次发作.1例额叶海绵状血管畸形患者术后出现对侧肢体肌力下降,经治疗后逐渐好转.无术后死亡患者.平均随访27.5个月(6～66个月),无海绵状血管畸形复发者.结论 脑多发海绵状血管畸形患者易并发癫痫.依据海绵状血管畸形部位和术中电生理监测,采用个体化致痫病灶切除及皮层热灼术或海马杏仁核扩大切除术可有效治疗脑多发海绵状血管畸形并发癫痫.
展开▼
