Objective To investigate the clinical and imaging features of hypertrophic olivary degeneration (HOD) secondary to brain-stem hemorrhage. Methods The clinical data of one patient with HOD secondary to brainstem hemorrhage was retrospectively analyzed. Re-sults The patient was hospitalized with paroxysmal and body involuntary jitter and other extrapyramidal symptoms. After admission, MRI scan showed bilateral inferior olive nucleus of medulla oblongata were localized hypertrophy. Conclusion The main clinical manifestation of HOD secondary to brainstem hemorrhage is extrapyramidal symptom. The imaging features are abnormal signals and localized hypertro-phy at inferior olive nucleus.%目的：探讨脑干出血继发肥大性下橄榄核变性(HOD)的临床及影像学特点。方法回顾性分析1例脑干出血继发HOD患者的临床资料。结果本例患者以阵发性全身不自主抖动等锥体外系症状就诊入院，入院后头颅MRI示延髓双侧下橄榄核区局限性肥大。结论脑干出血继发HOD的临床表现以锥体外系症状为主，影像学改变为下橄榄核区异常信号和局限性肥大。
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