目的 探讨高电位疗法治疗慢性偏头痛的有效性与安全性.方法 86 例符合纳入标准的慢性偏头痛患者者随机分为两组,治疗组(n=43)接受高电位治疗仪治疗,对照组(n=43)采用空白对照,疗程20 d.对痊愈的受试者停止治疗后随访4 周.采用简式McGill 疼痛问卷(MPQ)进行评定,记录治疗前后实验室检查结果.统计分析数据集的选择包括处理意向(ITT)及符合方案数据分析(PP).结果 治疗组和对照组对治疗后疼痛分级指数(PRI)、视觉模拟评分(VAS)和现有疼痛强度(PPI)有显著性差异(P<0.05).治疗组6 例、对照组1 例痊愈.随访4 周,治疗组与对照组均有1 例复发,疼痛程度无显著性差异.两组患者治疗前后血、尿、便常规,肝肾功能及心电图检查均无明显变化.结论 高电位治疗仪治疗慢性偏头痛效果较好,无副作用.%Objective To investigate the effect of high-voltage electrostatic therapy on chronic migraine. Methods 86 cases who met inclusion criteria were randomly divided into two groups: high-voltage group (n=43) was treated with high-voltage therapeutic device for 20 d. Control group (n=43) was blank control. The recovered cases were followed up for 4 weeks after cessation of treatment. They were assessed with McGill Pain Questionnaire (MPQ), and their results of laboratory tests were recorded before and after treatment. The data set analyzed included Intention-To-Treat, and per protocol. Results The differences between 2 groups were statistically significant in Pain Rating Index, Visual Analog Score and Present Pain Intensity after treatment (P<0.05). 6 patients in the treatment group and 1 patient in the control group recovered. During the 4-week follow-up, 1 case recured in each group, the intensity of pain was not statistically significant. There was no difference in the laboratory indice of blood, urine, stool routine, liver and kidney function (ALT, BUN, Cr) and ECG in both groups before and after treatment. Conclusion The high-voltage electrostatic therapy is effective and safe on chronic migraine.
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