Updated concepts on the pathophysiology and the clinical management of trauma hemorrhage and coagulopathy

Marc Maegele; Zheng-Tao Gu; Qiao-Bing Huang; Hong Yang

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Updated concepts on the pathophysiology and the clinical management of trauma hemorrhage and coagulopathy

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Uncontrolled hemorrhage and subsequent trauma-induced coagulopathy (TIC) are still the principle causes for preventable death after trauma and early detection and aggressive management have been associated with reduced mortality.Despite increasing knowledge about trauma resuscitation,best practice to treat this newly defined entity is still under debate.A synopsis of best current knowledge with reference to the updated European trauma guideline on the management of severe trauma hemorrhage and TIC is presented.The implementation of evidence-based local protocols and algorithms including clinical quality and safety management systems together with parameters to assess key measures of bleeding control and outcome is advocated.

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《中华创伤杂志（英文版）》 |2017年第3期|125-132|共8页
作者
Marc Maegele; Zheng-Tao Gu; Qiao-Bing Huang; Hong Yang;
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Department for Trauma and Orthopedic Surgery, Cologne-Merheim Medical Center(CMMC), University Witten/Herdecke(UW/H), Campus Cologne-Merheim,Ostmerheimerstr 200, D-51109 K(o)ln, Germany;

Institute for Research in Operative Medicine(IFOM), University Witten/Herdecke(UW/H), Campus Cologne-Merheim, Ostmerheimerstr 200, D-51109 K(o)ln, Germany;

Department of Intensive Care, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, PR China;

Department of Pathophysiology, Guangdong Provincial Key Laboratory of Shock and Microcirculation Research, Southern Medical University, Guangzhou 510515, PR China;

Department of Pathophysiology, Guangdong Provincial Key Laboratory of Shock and Microcirculation Research, Southern Medical University, Guangzhou 510515, PR China;

Department of Intensive Care, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, PR China;

Department of Pathophysiology, Guangdong Provincial Key Laboratory of Shock and Microcirculation Research, Southern Medical University, Guangzhou 510515, PR China;

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Updated concepts on the pathophysiology and the clinical management of trauma hemorrhage and coagulopathy

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