Expression of nuclear factor- κB in traumatic cataract

杨茜; 赵桂秋; 李倩; 刘相萍

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Expression of nuclear factor- κB in traumatic cataract

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＜正＞Objective: To study the differences in expression of nuclear factor-κB （ NF-κB ） between human traumatic cataract and normal lenticular epithelial cells. Methods: Total RNA of anterior capsule specimens was taken under the microscope from normal cadaveric eyes donors and those suffering from traumatic cataract to make semi-quantitative RT-PCR and conduct analysis of differences in expression of NF-κB between them. Results: As compared with the mean of 0.8337 in normal control group, the expression equivalent of NF-κB was 0.9074 for the lenticular epithelial cells in traumatic cataract sufferers, and the differences are of noticeable significance （t=2.447, P＜0.05） accordingly. Conclusions: NF-κB is likely a kind of transcription factor necessary to maintain metabolism of normal lenticular epithelial cells. Higher NF-κB available in the traumatic cataract sufferer’s lenticular epithelial cells means NF-κB is of possible relevance to occurrence and development of traumatic cataract.

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《中华创伤杂志：英文版》 |2006年第2期|86-90|共5页
作者
杨茜; 赵桂秋; 李倩; 刘相萍;
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作者单位

Department of Ophthalmology Affiliated Hospital of Qingdao University Medical School Qingdao 266000;

China;

Department of Ophthalmology Affiliated Hospital of Qingdao University Medical School;

Qingdao 266000;

China;

Department of Ophthalmology Affiliated Hosp;

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原文格式 PDF
正文语种 chi
中图分类眼损伤与异物;
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机译：核因子-κB;白内障;晶状体;上皮细胞;

Expression of nuclear factor- κB in traumatic cataract

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