目的 探讨射频消融(radiofrequency ablation,RFA)及微波消融(microwave ablation,MWA)两种方法治疗子宫肌瘤的临床疗效.方法 回顾性分析42例患者使用RFA或MWA进行子宫肌瘤热消融资料,比较两组患者消融术中生命体征变化状况、消融前后肌瘤缩小情况及患者生活质量,分析两种消融方法治疗子宫肌瘤的临床疗效及对相关并发症的影响.结果 23例行RFA治疗及19例行MWA治疗的患者术中生命体征变化状况、术中及术后疼痛视觉模拟评分(visual analogue scale,VAS)两组间差异均有统计学意义(P＜0.05);使用两种方法消融后,肌瘤较术前均明显缩小,差异有统计学意义(P＜0.05),但两种消融方法的肌瘤体积变化差异无统计学意义(P＞0.05);消融后,两组患者临床症状明显改善,组间生活质量评分差异无统计学意义(P＞0.05).结论 RFA及MWA消融子宫肌瘤均有较好的疗效,RFA的不良反应较MWA小.%Objective To investigate the efficiency of radiofrequency ablation (RFA) and microwave ablation (MWA) in treating uterine leiomyoma.Methods The clinical data of thermal ablation with RFA and MWA were retrospectively analyzed in 42 patients.All patients were followed up at least 12 months to observe the therapeutic effects after the treatment.The changes of vital signs and the size of uterine leiomyoma,the score of uterine leiomyoma symptom and quality of Iife(UFS-QOL) were compared after RFA or MWA,the two thermal ablations techniques of clinic efficiency and influence on complications were analyzed.Results 23 patients received treatment of RFA and 19 patients received MWA,the visual analogue scale(VAS)during operation and postoperation were statistically significant differences between the two groups(P ＜0.05).The sizes of uterine leiomyoma were significantly reduced after the thermal ablation,the differences of volume within two groups in different time were statistics significance(P ＜0.05),but there were no statistics significance differences between two groups (P ＞0.05).The symptoms in two groups were improved significantly after treatment and the scores of UFS-QOL were no statistics significance differences between two groups (P ＞0.05).Conclusions Both of RFA and MWA have significant clinic efficiency in treating uterine leiomyoma.Compared with MWA,RFA with lower adverse reactions during operation and postoperation.
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