目的 比较分析声触诊组织成像定量技术(VTIQ)取样框大小对乳腺结节剪切波速度(SWV)测值的影响,旨在优化VTIQ技术在乳腺疾病中的检查方案.方法 研究72个结节回声均匀的乳腺结节超声影像资料,所有患者术前均行常规超声与VTIQ弹性成像检查,手术病理证实所有结节均为良性结节.术前进行VTIQ检查时设置三种不同规格取样框,大小分别为小取样框10 mm×10 mm、中取样框20 mm×20 mm及大取样框25 mm×38 mm,所有结节均在取样框内,根据结节大小选多个感兴趣区测SWV,然后分别计算结节的SWVmax、SWVmin、SWVmean和SWVmedian,分析VTIQ技术不同大小取样框对乳腺结节SWV测值的影响.结果 72个结节三种不同大小取样框下的SWVmax、SWVmin、SWVmean、SWVmedian比较均有显著差异(P值＜0.001),各取样框间两两比较除了中取样框与大取样框间SWVmin无统计学差异外(P=0.074),其余两两比较均有显著性差异(P＜0.05),并且小取样框测值最大.结论 取样框大小直接影响SWV测值,小取样框SWV测值最大.%Objective Shear wave elastography is a new method of obtaining quantitative tissue elasticity data during breast ultrasound examinations.This study compared the shear wave velocity values (SWVs) on breast nodules within different sampling box of the Virtual Touch Tissue Imaging Quantification (VTIQ) technique.The aims of this study were (1) to test the hypothesis that sampling box selection would definitively impact the elasticity measure ments,and (2) to optimize the VTIQ technique examination protocol in breast disease.Methods Ultrasound image data of 72 breast nodules were collected before surgery.All the patients underwent Conventional US and VTIQ elastography.VTIQ was performed with three different sampling boxes to measure the SWVs.The small sampling box,moderate sampling box and large sampling box were 10 mm× 10 mm,20 mm×20 mm,and 25 mm×38 mm,respectively.Multiple SWVs within each lesion were obtained according to the size of the nodule.The SWVmax,SWVmin,SWVmean and SWVmedian were calculated respectively.Results Significant differences were found between the SWVmax,SWVmin,SWVmean and SWVmedian with three different sampling box (all P＜0.001).The SWVmin within the moderate sampling box was bigger than that within the large sampling box,whereas no significant discrep ancy among them was found (P=0.074).The difference of SWVs between any other two sampling box was remarkable (all P＜0.05),and the SWVmax,SWVmean,SWVmedian within the small sampling box were the biggest.Conclusions The size of the sampling box straightly affects the SWV measurement,and the small sampling box has the biggest SWV.
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