Objective To explore the risk factors of metabolic syndrome ( MS ) in simple obesity children. Methods Blood pressure was measured in obesity group and control group, and fasting blood sugar and blood lipid of two groups were determined by automatic biochemical analyzer. MS of children was analyzed according to criteria of International Diabetes Federation ( IDF ). Results Eighteen of 51 simple obesity children ( 35. 29% ) had MS, including 14 boys ( 42.42% ) and 4 girls ( 22. 22% ). Analysis of individual components of MS showed that there were 22 (43. 14% ) cases of hypertriglyceridemia, 19(37.25% )oflowHDL-C, 14(27.45% ) of hypertension and 3(5.88% ) of high blood sugar. There were significant differences in the levels of serum triglycerides, total cholesterol, low-density lipoprotein and high-density lipoprotein between obesity group and control group ( all P < 0.05 ). Conclusion Controlling children obesity is one of the key factors to prevent MS and decrease the incidence rate of cardiovascular disease and type 2 diabetes mellitus in adult.%目的 探讨单纯性肥胖儿童代谢综合征危险因素.方法 肥胖组和对照组测血压,并采用生化自动仪测定血糖和血脂.采用国际糖尿病联盟诊断标准对肥胖儿童进行代谢综合征的分析.结果 ①51例单纯性肥胖儿童中代谢综合征18例,检出率为35.29%,其中男14例(42.42%),女4例(22.22%);②代谢综合征单项组分分析显示,高甘油三酯血症22例(43.14%),低高密度脂蛋白胆固醇血症19例(37.25%),高血压14例(27.45%),高血糖3例(5.88%);③肥胖组儿童血清甘油三酯、总胆固醇、低密度脂蛋白、高密度脂蛋白与对照组比较,均有统计学差异(均P<0.05).结论 控制儿童肥胖的发生和发展是预防代谢综合征,降低成人期心血管疾病和2型糖尿病发病率的关键因素之一.
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