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女性体检人群高尿酸血症及其伴发疾病分析

         

摘要

Objective To investigate prevalences of hyperuricemia and concomitant diseases among women who received health examination so as to show importance of serum uric acid examination. Methods In cluster sampling method, 6 207 women aged over 20 years who completed all checkup items and had complete data were extracted from health examination database of the hospital in a period from 2006 to 2008. Then serum level of uric acid of the women in different age groups and age-based prevalence of hyperuricemia were analyzed. And BMI, blood sugar/blood fat of the women and prevalences of hyperuricemia, diabetes mellitus (DM) and hyperlipemia in hyperuricemia group and the normal uric acid group were compared. Results The prevalence of hyperuricemia among women who received health examination was 6.72%, and showed a rapid increasing tendency with increase in age of the women, especially, the prevalences of hyperuricemia among the women aged 40~ to 70 ~ years groups (5.56%, 9.57%, 11.72%, 23.26% respectively) wexe higher than that in both groups of 20 ~ years (2.08%) and 30 ~ years(2.56% ) significantly(x2 = 17.188, 48.460, 63.390, 154.787, 17.920,60.478, 79.293, 201. 710 respectively, all P < 0.001 ). The prevalence rates of obesity, hypertension, hyperglycemia,hypercholesterolemia and hypertriglyceridemia in the hyperuricemia group were higher than those in the normal group and the differences were significant(x2 = 29.719, 22.659, 12.292, 96.967, 417.309 respectively, all P < 0.001 ). Conclusion The hyperuricemia is rented to obesity, hypertension, hyperglycemia and hyperlipemia. It’s indispensable to screen hyperuricemia and concomitant diseases among women who receive health examination, which would prevent development of cerebrovascular diseases as early as possible.%目的 调查分析女性体检人群高尿酸血症的患病及合并相关疾病情况,说明女性人群血尿酸检查的重要性.方法 从2006~2008年在第四军医大学附属西京医院健康体检资料中整群抽取20岁以上完成全部项目检查并且资料完整的女性6 207例,分析不同年龄组女性的血尿酸水平及高尿酸血症的分布情况,对高尿酸血症组与正常尿酸组的身体质量指数、血糖、血脂各项指标以及患病率进行比较.结果 女性健康体检人群高尿酸血症患病率为6.72%,并且随年龄增长呈快速增长趋势,特别是从40~岁开始,各年龄组(40~、50~、60~、70~)高尿酸血症患病率(5.56%、9.57%、11.72%、23.26%)与20~(2.08%)和30~发组患病率(2.56%)相比有显著性差异(χ2值分别为17.188、48.460、63.390、154.787及17.920、60.478、79.293、201.710,均P<0.001);高尿酸血症组与正常尿酸组研究对象肥胖、高血压、高血糖、高胆固醇血症、高甘油三酯血症患病率间比较均有显著性差异(χ2值分别为29.719、22.659、12.292、96.967、417.309,均P<0.001).结论 女性体检人群高尿酸血症与肥胖、高血压、高血糖及高血脂有关,加强女性健康体检人群高尿酸血症及其伴发疾病的筛查必不可少,可及早预防心脑血管疾病的发生.

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