首页> 中文期刊> 《中国医学文摘:内科学分册(英文版)》 >The effects of curcumin on the 19000 Mycobacterium tuberculosis protein-induced inflammatory and apoptotic reaction and the expression of p38 mitogen-activated protein kinases in WBC264-9C macrophages

The effects of curcumin on the 19000 Mycobacterium tuberculosis protein-induced inflammatory and apoptotic reaction and the expression of p38 mitogen-activated protein kinases in WBC264-9C macrophages

         

摘要

Objective By using the cell wall component of Mycobacterium tuberculosis 19 000 lipoprotein(P19)and curcumin(CUR)acting on the human macrophage cell line WBC264-9C,and by the blocking of the p38 mitogen-activated protein kinases(p38 MAPK)signaling pathway,we wanted to investigate the effect of curcurmin on P19-induced inflammatory responses and apoptosis in human macrophages and the potential underlying molecular mechanisms.Methods P19 and CUR were used to

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