Zebrafish (Danio rerio) is a simple biological labora-tory animal, with similar biological structure and physiological functions to mammals. Almost transparent embryos, in vitro de-velopment of embryos and up to 87% of human genetic similari- ties enable a wide application of zebrafish in the field of pharma-ceutical research. In this paper, we have studied the application of zebrafish in drug metabolism, the research of Chinese medi-cine, the evaluation of drug toxicology and safety, the screening of drugs and the discovery of new drugs, the research of regener- ative drugs, so as to provide new ideas of zebrafish in the field of pharmacy.%斑马鱼(Danio rerio)是一种简单的生物实验动物,具有和哺乳动物相似的生物结构和生理功能.几乎透明的胚胎、胚胎的体外发育以及与人类高达87%的基因相似性,使得斑马鱼被广泛用于药学领域的研究.该文综述了近年来国内外斑马鱼在药物代谢研究、中药研究、药物毒理学与安全性评价、药物筛选与新药发现、再生药物研究等药学领域,为斑马鱼在药学领域的应用研究提供新思路.
展开▼
