血管钙化是一个与骨发育相似的过程,血管异常钙化与动脉粥样硬化以及血管顺应性降低等病变密切相关,导致血管钙化的主要原因是血管壁的钙磷过量异常沉积。血管钙化的形成受多种因素的共同调节,该文从分子机制、化学机制、代谢因素及炎症因素探讨影响血管钙化形成的因素,并对中药防治血管钙化方面的国内外研究进展进行综述。%Vascular calcification is a process similar to bone de-velopment, which is excessively abnormal deposition of calcium and phosphate in blood vessel wall. It is a sign of early athero-sclerosis formation, and can reduce the atherosclerotic vascular compliance. The common regulation of vascular calcification is affected by many factors. This article discusses the formation of vascular calcification from the molecular mechanism, the chemi- cal mechanism and metabolic factors. It also reviews the progress of the prevention of vascular calcification by traditional Chinese medicine.
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