Coupling Effect of Ion Channel Clusters on Calcium Signalling

TANG Jun; JIA Ya; YI Ming; MA Jun; YU Guang

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Coupling Effect of Ion Channel Clusters on Calcium Signalling

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@@ Based on a modified intracellular Ca2+ model involving diffusive coupling of two calcium ion channel clusters,the effects of coupling on calcium signalling are numerically investigated.The simulation results indicate that the diffusive coupling of clusters together with internal noise determine the calcium dynamics of single cluster,and for either homogeneous or heterogeneous coupled clusters,the synchronization of clusters,which is important to calcium signalling,is enhanced by the coupling effect.

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《中国物理快报：英文版》 |2008年第3期|1149-1152|共4页
作者
TANG Jun; JIA Ya; YI Ming; MA Jun; YU Guang;
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Department of Physics and Institute of Biophysics,Huazhong Normal University,Wuhan 430079;

College of Science,China University of Mining and technology,Xuzhou 221008;

Department of Physics and Institute of Biophysics,Huazhong Normal University,Wuhan 430079;

Department of Physics and Institute of Biophysics,Huazhong Normal University,Wuhan 430079;

Department of Physics and Institute of Biophysics,Huazhong Normal University,Wuhan 430079;

Department of Physics and Institute of Biophysics,Huazhong Normal University,Wuhan 430079;

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中图分类物理学;
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Coupling Effect of Ion Channel Clusters on Calcium Signalling

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