首页> 中文期刊> 《中国物理快报:英文版》 >Effects of Substrate Hydrophobicity/Hydrophilicity on Height Measurement of Individual DNA Molecules

Effects of Substrate Hydrophobicity/Hydrophilicity on Height Measurement of Individual DNA Molecules

         

摘要

Effects of substrate hydrophobicity/hydrophilicity on height measurement of individual ds-DNA molecules are investigated with tapping mode atomic force microscopy (TMAFM) and vibrating mode scanning polarization force microscopy (VSPFM). The measured heights of ds-DNA on hydrophobic highly oriented pyrolytic graphite (HOPG) are remarkably less than those on hydrophilic bare mica and Ni2+ treated mica in both TMAFM and VSPFM. By analysing the results, we propose that the hydrophobicity/hydrophilicity of substrate can greatly influence the height measurement of DNA molecules.

著录项

  • 来源
    《中国物理快报:英文版》 |2007年第3期|644-647|共4页
  • 作者单位

    Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800;

    Graduate School of the Chinese Academy of Sciences, Beijing 100080;

    Department of Physics, Ningbo University, Ningbo 315211;

    Tianjin University of Science and Technology, Tianjin 300040;

    Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800;

    Bio-X Life Science Research Center, Shanghai Jiao Tong University, Shanghai 200030;

    Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800;

    Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800;

    Bio-X Life Science Research Center, Shanghai Jiao Tong University, Shanghai 200030;

  • 原文格式 PDF
  • 正文语种 chi
  • 中图分类 物理学;
  • 关键词

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