Objective To investigate the clinical application and curative effect of Carbon Nano-particles in curative resection of mid-low rectal cancer .Methods 26 patients with mid-low rectal cancer were divided equally into carbon nano-particle group and routine group .The labeling group were injected with carbon nano-particles 20~24 hours before operation and treated with TME laparoscopic radical resection .The data of lymph nodes detected in the two groups were compared .Results (1)Total number of lymph nodes detected in the labeling group was higher than that of the routine group (287 vs .124 ,P<0 .05) .(2)The labeling group had higher average lymph nodes detected per patient (22 .12 ± 3 .50 vs .9 .56 ± 1 .50 ,P< 0 .05) ,as well as higher average lymph nodes smaller than 5mm per patient(9 .18 ± 1 .41 vs .3 .50 ± 0 .82 ,P<0 .05) .(3)The metastasis rate of lymph nodes detected in la-beling group lacked statistical significance as compared with that of the routine group (3 .10 ± 0 .37 vs .2 .62 ± 0 .25 ,P>0 .05) .Con-clusion Adoption of carbon nano-particle in curative resection of rectal cancer can increase the number of lymph nodes detected ,re-veal more accurately the metastasis situation of lymph nodes ,facilitate the resection of lymph nodes and rectal cancer during the op-eration ,and provide guidance for postoperative clinical staging and treatment .% 目的探讨纳米炭示踪剂在中低位直肠癌根治术中的临床应用及效果。方法选择26例中低位直肠癌患者，分为纳米炭示踪剂注射组和常规组，纳米炭示踪剂注射组术前20～14 h注射，根据T M E原则行腹腔镜下根治术，术后分析比较两组检获淋巴结情况。结果注射组检获淋巴结总数287枚，高于常规组124枚（ P＜0．05）；平均淋巴结检获数（22．12±3．50）枚/例，高于常规组（9．56±1．50）枚/例（ P＜0．05）；平均小于5 m m淋巴结检获数（9．18±1．41）枚/例，高于常规组（3．50±0．82）枚/例（ P＜0．05）；平均阳性淋巴结阳性检获数（3．10±0．37）枚/例，与常规组（2．62±0．25）枚/例比较差异无统计学意义（ P＞0．05）。结论纳米炭示踪剂应用于中低位直肠癌根治术能提高淋巴结检获数，从而更准确地反映患者的淋巴结转移情况，能为术后临床分期、后期治疗提供帮助；能为术中清除淋巴结以及肿瘤远端切除提供指导。
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