Objective To investigate the effect of transurethral bipolar plasma kinetic prostatectomy(TUPKP)and orchidectomy combined with intermittent androgen deprivation(IAD) on metaphase-advanced prostate cancer. Methods 40 cases with metaphase-advanced prostate cancer received the treatment of transurethral bipolar plasma kinetic prostatectomy and orchidectomy combined with intermittent androgen deprivation. Results There were significant differences in international prostate symptom score(IPSS) , quality of life(QOL) , maximum flow rate(MFR) , residual urine volume(RV) , prostate specific antigen(PSA) and volume of prostate between before operaition and after operation(P＜0. 01). Conclusion The effect of transurethral bipolar plasma kinetic prostatectomy and orchidectomy combine with intermittent androgen deprivation on metaphase-advanced prostate cancer is obvious and it can improve the life quality of patients,so it is worthy of applying and spreading in clinic.%目的 观察经尿道等离子前列腺电切术(TUPKP)和睾丸切除术联合间歇性雄激素抑制(IAD)治疗中晚期前列腺癌(Pca)的疗效.方法 40例中晚期Pca患者行TUPKP治疗并且行睾丸切除术和IAD治疗.结果 6个月后,国际前列腺症状评分(IPSS)、生活质量评分(QOL)、最大尿流率(MFR)、残余尿量(RV)、前列腺特异抗原(PSA)、前列腺体积等与术前比较差异有统计学意义(P＜0.01).结论 TUPKP和睾丸切除联合IAD治疗中晚期Pca的疗效确切,明显提高患者生活质量,值得临床推广应用.
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