Traditional production planning models do not involve constraints for process operations. In order to obtain the optimal refinery production planning and ensure that unit operating conditions of optimization plan can be achieved simultaneously, production planning and process operations were optimized and integrated for petrochemical industries.The operating conditions were obtained using process simulation software with the optimal production plan. The model was illustrated by a case study of refinery. The results demonstrated that the proposed method can ensure the accessibility of production plan, optimize the plan a greater role in the production practice of production.%传统的炼油企业生产计划优化与过程操作优化往往是分离的，从而造成生产计划优化系统制定出的生产方案可能在实际的生产装置操作上无法实现的情况。为了确保石化企业生产计划制定的方案可行的同时实现过程装置操作优化，基于流程模拟软件建立了常减压蒸馏装置生产计划与过程操作的集成优化策略，并提出了该优化策略的有效寻优方法。该方法通过流程模拟软件验证生产计划的可达性，不断修正生产计划关键变量的优化区间，在求得生产计划最优解的同时确定装置的工艺操作条件。以某炼油厂常减压蒸馏装置炼油为例验证提出的集成优化方法，案例证明该集成策略不仅确保生产计划在实际生产的可操作性，还得到了生产计划与过程装置操作的同步优化。
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